マクロジェンは、様々なシーケンシングプラットフォームに特化した解析ソフトウェアを利用して、 Standard Data Report と解析結果を提供します。 専門の解析サービスチームがお客様の多様なニーズに対応するカスタム解析も提供できます。また、遺伝変異の確認から比較解析に至るまで、付加的な解析を行っています。
Sequence Methodology |
Sequence Only |
Standard Analysis |
Special Analysis |
De novo Sequencing |
FASTQ |
De novo assembly |
1. Variant Calling (SNP, In/Del)
2. Gene Prediction
3. Gene Annotation
|
Whole Genome Resequencing |
FASTQ |
1.Alignment and summary of data production
2.Variant Calling (SNP, In/Del) and Annotation
|
1.Comparative Analysis
2.Disease Analysis
3.Structural Variation (CNV and SV) and Annotation
|
Exome /Target Sequencing |
FASTQ |
1.Alignment and summary of data production 2.Variant Calling (SNP, In/Del) and Annotation |
1.Comparative Analysis 2.Disease Analysis |
Transcriptome Resequencing |
FASTQ |
1.Expression Profiles 2.Differentially Expressed Genes (DEGs) 3.Fusion Gene |
1.Gene Set Analysis 2.Variant Calling and Annotation 3.Comparative Analysis |
Transcriptome De Novo Sequencing |
FASTQ |
1.De novo Assembly 2.Alignment and Statistics 3.Expression Profiling |
1.Gene Annotation 2.Gene Set Analysis 3.Variant Calling (SNP, In/Del) and Annotation |
smRNA Sequencing |
FASTQ |
1.Expression Profiles 2.Novel smRNA 3.Differentially Expressed miRNA |
1.Target Prediction of Known and Novel miRNA 2.Gene Set Analysis 3.Comparative Analysis |
Metagenome 16s rDNA Sequencing |
FASTQ |
1.OTU Counting 2.OTU Diversity |
Comparative Analysis |
Metagenome Shotgun Sequencing |
FASTQ |
1.De novo assembly 2.Blastx |
1.Gene Prediction
2.OTU counting (16S rDNA or other housekeeping genes)
3.Function assignment to each gene candidate
4.Constructing metabolic pathways
5.Statistical analysis of two or more meta-genomic samples
|
ChIP Sequencing |
FASTQ |
1.Enrichment Peak Profiles and Gene Annotation
2.Differentially Enriched Peaks and Gene Annotation
3.Multiple Alignment and Consensus Motif
|
1.Gene Set Analysis
2.Comparative Analysis
|
MBD Sequencing |
FASTQ |
1.Global Methylation Profiles
2.Specific Methylation Profiles
- Protein-Coding Genes
- CG Islands
- Several Repeated Sequences
3. Differentially Methylation Regions (DMR)
|
1.DMR-Associated Genes
2.Gene Set Analysis
3.Comparative Analysis
|